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Myopic (Peri)papillary Changes and Visual Field Defects.

Adèle Ehongo1, Artémise Dugauquier1, Nacima Kisma1

  • 1Ophthalmology Department, Erasmus Hospital, Brussels, 1070, Belgium.

Clinical Ophthalmology (Auckland, N.Z.)
|November 7, 2023
PubMed
Summary
This summary is machine-generated.

Posterior intrachoroidal cavitation (PICCs) are associated with visual field defects in myopic eyes. Lower ovality index (OI) was the key factor discriminating eyes with PICCs from those without, suggesting structural changes impacting vision.

Keywords:
gamma peripapillary atrophyglaucomalamina cribrosa defectsmyopic complicationsovality indexperipapillary intrachoroidal cavitationperipapillary staphylomavisual field defects

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Research

Background:

  • Myopic eyes with gamma peripapillary atrophy and peripapillary staphyloma present complex structural variations.
  • Understanding the presence of posterior intrachoroidal cavitation (PICCs) and its impact on visual function is crucial in high myopia.

Purpose of the Study:

  • To analyze visual field defects (VFDs) in myopic eyes with and without PICCs.
  • To identify factors that discriminate between eyes with PICCs and those without (combinations).

Main Methods:

  • Optical coherence tomography was used to sort eyes based on the presence or absence of PICCs.
  • Visual field defects were assessed using the Humphrey Field Analyzer 3 (SITA standard).
  • Ovality index (OI), lamina cribrosa defects (LCDs), and their distribution were analyzed and compared between groups using multivariate logistic regression.

Main Results:

  • Eyes with PICCs showed a significantly higher prevalence of VFDs (65%) compared to combinations (p < 0.001).
  • Posterior intrachoroidal cavitation (PICCs) and lamina cribrosa defects (LCDs) predominantly occurred in the inferotemporal sector (sector B).
  • A significantly lower mean ovality index (OI) was observed in eyes with PICCs (p < 0.001), identified as the sole significant discriminating factor.

Conclusions:

  • The lower mean OI in eyes with PICCs indicates a gradation of structural changes, potentially explaining the higher proportion of VFDs.
  • The inferotemporal predominance of PICCs suggests its role in diagnostic uncertainty for glaucoma in high myopia.
  • The inferotemporal sector's vulnerability to damage in myopic eyes warrants further investigation due to the high proportion of PICCs and LCDs.