Geroscience: Aging and Oral Health Research

Area of Science:

• Gerontology and Dental Research
• Translational Science
• Health Span Research

Background:

• Aging research identifies interventions targeting "hallmarks of aging" to delay disease onset.
• Oral health is increasingly recognized as integral to overall health and longevity.
• Geroscience links aging processes to oral health, impacting systemic conditions.

Purpose of the Study:

• Summarize key findings from the "Geroscience: Aging and Oral Health Research" session.
• Highlight the translational research spectrum from basic science to health policy.
• Emphasize the need for improved oral health span and equity in older adults.

Main Methods:

• Review of presentations from a 3-part session at the 2023 American Association for Dental, Oral, and Craniofacial Research meeting.
• Discussion of research spanning molecular mechanisms, behavioral science, and healthcare delivery.
• Synthesis of data on aging, oral health, and systemic disease connections.

Main Results:

• Common molecular pathways link aging and oral cancer; periodontal microflora may influence Alzheimer's disease.
• Loneliness, isolation, and cognitive decline impact oral health, eating ability, and systemic health in older adults.
• Significant barriers exist in accessing dental care for older adults, necessitating innovative delivery models.

Conclusions:

• Interventions targeting aging hallmarks can improve oral health and prevent disease.
• Addressing social determinants and integrating medical-dental data is crucial for oral health equity.
• Future research should focus on improving oral health span, reducing disparities, and enhancing care access through policy and technology.