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Updated: Jul 11, 2025

Digital Inline Holographic Microscopy DIHM of Weakly-scattering Subjects
Published on: February 8, 2014
Minimal data requirement for realistic endoscopic image generation with Stable Diffusion.
Joanna Kaleta1, Diego Dall'Alba2,3, Szymon Płotka1,4,5
1Sano Centre for Computational Medicine, Krakow, Poland.
This study introduces a novel image-to-image translation method using Stable Diffusion to create realistic surgical data from synthetic inputs. This approach enhances deep learning models for computer-assisted surgery guidance systems.
Area of Science:
- Medical Imaging
- Computer-Assisted Surgery
- Artificial Intelligence
Background:
- Computer-assisted surgical systems enhance surgical procedure execution and outcomes.
- Deep learning models are crucial for these systems but require extensive, well-annotated data.
- Generating synthetic data is a viable solution to data limitations, but minimizing the domain gap between real and synthetic data is essential.
Purpose of the Study:
- To develop a method for translating synthetic images into realistic ones for training surgical AI.
- To improve the generalizability of deep learning models in computer-assisted intervention guidance systems.
Main Methods:
- A novel image-to-image translation technique based on a Stable Diffusion model is proposed.
- The method utilizes synthetic data as input to generate realistic medical images.
- Control networks are incorporated for finer control over image details and reduced input data requirements.
Main Results:
- The method was successfully applied to laparoscopic cholecystectomy datasets.
- It achieved a mean Intersection over Union (IoU) of 69.76%, significantly outperforming baseline methods (42.21%).
Conclusions:
- The proposed image translation method effectively generates realistic images from synthetic data.
- This advancement facilitates the training of deep learning models that generalize better to real-world surgical scenarios.
- The approach holds promise for improving the performance and reliability of computer-assisted surgical guidance systems.
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