Related Experiment Video

Updated: Jul 11, 2025

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

306

Prevalence of aortic aneurysms and dissections in patients with systemic vessel aneurysms and dissections; matched

Jihye Song1, Yong Cheol Lim1, Do Jung Kim2

  • 1Department of Neurosurgery, Ajou University School of Medicine, Ajou University Hospital, Suwon, Republic of Korea.

Frontiers in Cardiovascular Medicine
|November 8, 2023
PubMed

Insights

Patients with other systemic vessel aneurysms and dissections (OVAD) have a 37.56 times higher prevalence of aortic aneurysms and dissections (AAD). This suggests viewing aneurysms as systemic diseases for better understanding and treatment.

Area of Science:

  • Vascular Surgery
  • Cardiovascular Research
  • Epidemiology

Background:

  • Aneurysms in systemic arteries are rare, with limited understanding of their connection to aortic aneurysms.
  • Aortic aneurysms and dissections (AAD) and other systemic vessel aneurysms and dissections (OVAD) are distinct but potentially related vascular conditions.

Purpose of the Study:

  • To evaluate the prevalence of AAD in patients diagnosed with OVAD.
  • To identify potential risk factors associated with the co-occurrence of AAD and OVAD.

Main Methods:

  • A cross-sectional study utilizing a nationwide representative cohort from the Korea National Health Insurance Service-National Sample Cohort database.
  • Defined OVAD as aneurysms and dissections in systemic vessels, excluding those in the brain and aorta.
  • Compared 690 OVAD patients with 2,760 matched non-OVAD controls, using chi-squared tests and logistic regression for analysis.

Main Results:

  • The prevalence of AAD was significantly higher in the OVAD group (10.6%) compared to the non-OVAD group (0.3%).
  • Patients with OVAD had an adjusted odds ratio of 37.56 for concurrent AAD.
  • Higher adjusted odds ratios for AAD were observed in females, individuals aged 60 years and older, and those without hypertension, diabetes mellitus, or dyslipidemia. AAD prevalence also varied significantly by the specific site of OVAD.

Conclusions:

  • The study highlights a substantially increased prevalence of AAD in patients with OVAD, suggesting aneurysms may be systemic diseases.
  • Further research into the pathophysiology of aneurysms is warranted to elucidate the relationship between AAD and OVAD.
Abstract

Keywords:
aneurysmaortic aneurysmaortic diseaseaortic dissectionperipheral artery disease

More Related Videos

Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta07:12

Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta

Published on: September 8, 2023

2.4K
Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model09:32

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model

Published on: February 23, 2020

6.2K

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
10
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
11
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
9
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
8
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
10
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
10