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Untethered Microgrippers for Precision Medicine.
Huaijuan Zhou1, Shengchang Zhang2, Zijian Liu2
1Advanced Research Institute of Multidisciplinary Sciences, Beijing Institute of Technology, Beijing, 100081, China.
Small (Weinheim an Der Bergstrasse, Germany)
|November 9, 2023
Summary
Untethered microgrippers are tiny robots revolutionizing medicine. This review details their design, control, and applications in precise diagnosis and minimally invasive treatments.
Area of Science:
- Biomedical Engineering
- Micro/Nanorobotics
Background:
- Untethered microgrippers are motile miniaturized machines (micrometer-scale).
- They offer advantages over tethered devices for accessing difficult anatomical regions.
- Their potential spans cell manipulation, targeted drug delivery, biopsy, and minimally invasive surgery.
Purpose of the Study:
- To review the latest advancements in untethered micrometer-scale grippers.
- To discuss design principles, fabrication techniques, and working mechanisms.
- To highlight applications in precise medicine and future perspectives.
Main Methods:
- Review of current literature on untethered microgrippers.
- Introduction to shape-morphing and actuation mechanisms.
- Discussion of design, fabrication, and application strategies.
Main Results:
- Numerous medical microgrippers have been developed with explored applications.
- Key design considerations include materials, size, microarchitecture, and morphology.
- Shape-morphing and actuation methods are crucial for controlled locomotion.
Conclusions:
- Untethered microgrippers are vital for precise medical tasks due to their unique characteristics.
- Continued development in design and fabrication will enhance their role in precise medicine.
- Future research will focus on advancing their capabilities for complex medical interventions.

