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Updated: Jul 11, 2025
Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
Published on: February 17, 2013
Experience of using coronary perfusion balloon catheter for acute middle cerebral artery occlusion
Shu Sogabe1, Tatsuya Haboshi1, Izumi Yamaguchi1
1Department of Neurosurgery, Institute of Biomedical Biosciences, Tokushima University Graduate School, Tokushima, Japan.
Insights
A coronary perfusion balloon effectively treated acute middle cerebral artery occlusion caused by atherosclerosis. This innovative angioplasty technique achieved successful recanalization and favorable clinical outcomes in a challenging case.
Area of Science:
- Neurology
- Interventional Cardiology
- Vascular Surgery
Background:
- Atherosclerosis can lead to acute occlusion of major cerebral arteries, such as the middle cerebral artery (MCA).
- Large vessel occlusion (LVO) in the MCA poses a significant risk of stroke and neurological deficit.
- Intracranial atherosclerotic disease is a common cause of ischemic stroke, particularly in certain populations.
Background:
We present the case of an individual with acute occlusion of the middle cerebral artery caused by atherosclerosis. The patient underwent angioplasty using a coronary perfusion balloon, which resulted in a favorable clinical outcome.
Case Description:
A 66-year-old male patient presented with an acute onset of right hemiplegia and dysarthria. Magnetic resonance imaging revealed an occlusion of the left middle cerebral artery, and alteplase was administered, followed by a mechanical thrombectomy and intracranial balloon catheter angioplasty. Due to restenosis, a coronary perfusion balloon catheter was used for a 15-minute angioplasty procedure while maintaining the perfusion. This treatment approach led to the recanalization of the artery and favorable clinical outcomes.
Conclusion:
The coronary perfusion balloon may represent a viable therapeutic alternative for the management of refractory intracranial atherosclerotic large vessel occlusion.
