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Nonpharmacological interventions for 'no-option' refractory angina patients
Yoav Paz1, Yair Levy2, Liza Grosman-Rimon3
1General Intensive Care Unit, Sourasky Medical Center, Tel Aviv, Israel, affiliated with Sackler Faculty of Medicine, Tel Aviv University.
Insights
Refractory angina pectoris (RAP) is challenging to manage. This review explores interventional treatments for chronic chest pain due to coronary artery disease (CAD), including current and investigational therapies.
Area of Science:
- Cardiology
- Interventional Cardiology
- Regenerative Medicine
Background:
- Refractory angina pectoris (RAP) presents as chronic chest pain from coronary artery disease (CAD).
- Increasing prevalence of RAP is linked to an aging population and better CAD survival rates.
- Managing RAP poses significant clinical challenges.
Conclusions:
- A range of interventional options exist for refractory angina pectoris.
- The management of RAP is evolving with new therapeutic avenues.
- Further research into novel treatments like cell therapies is warranted.
Abstract:
Refractory angina pectoris (RAP) defined as chronic anginal chest pain because of coronary artery disease (CAD) is a major problem. The increase in the number of patients with RAP in recent years is because of the increasing aging population and improved survival rates among patients with CAD. Management of patients with RAP is often extremely challenging. In this review, we present several interventional approaches for RAP, including device therapies, lifestyle intervention, and cell therapies. Some of these treatments are currently used in the management of RAP, whereas other treatments are under investigation.
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