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Updated: Jul 11, 2025

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[The possibilities of Mexidol usage in neuropediatrics]

N N Zavadenko1, N Yu Suvorinova1, A N Zavadenko1

  • 1Pirogov Russian National Research Medical University, Moscow, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|November 9, 2023
PubMed

Insights

Mexidol (ethylmethylhydroxypyridine succinate) shows promise in treating pediatric neurological conditions like ADHD and developmental delays. Further clinical trials are recommended to explore its full potential in neuropediatrics.

Area of Science:

  • Neurology
  • Pharmacology
  • Pediatrics

Context:

  • Mexidol (ethylmethylhydroxypyridine succinate) is a neurometabolic drug gaining traction in pediatric neurology.
  • Its efficacy has been observed in conditions such as ADHD, hypoxic-ischemic encephalopathy, and post-neurosurgical neurodevelopmental delays.

Purpose:

  • To review the current applications and potential of Mexidol in neuropediatrics.
  • To highlight the need for further clinical trials based on evidence-based medicine principles.

Summary:

  • Mexidol demonstrates positive therapeutic effects in children with various neurological and neurodevelopmental disorders.
  • These include attention deficit hyperactivity disorder (ADHD), perinatal central nervous system damage, and neurodevelopmental issues post-congenital heart defect surgery.
  • Its multimodal action supports its use in neuroinfections and post-traumatic epilepsy.

Impact:

  • Mexidol offers a promising therapeutic option for a range of pediatric neurological conditions.
  • Expanding its indications through rigorous clinical trials could significantly benefit neuropediatric patient care.

Keywords:
Mexidol (ethylmethylhydroxypyridine succinate)attention deficit hyperactivity disorderchildrenencephalitishypoxic-ischemic encephalopathymeningitisneurodevelopmental delaypost-traumatic epilepsytreatment

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