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Development and validation of Join Clinical Trial Questionnaire (JoinCT)
Shirin Hui Tan1, Teck Long King1, Shirley Siang Ning Tan1,2
1Clinical Research Centre, Sarawak General Hospital, Ministry of Health, Kuching, Sarawak, Malaysia.
Asia-Pacific Journal of Clinical Oncology
|November 9, 2023
Summary
The Join Clinical Trial Questionnaire (JoinCT) effectively measures factors influencing patient willingness to join clinical trials. Key factors identified include knowledge, perceived benefits, risks, and confidence.
Area of Science:
- Clinical research methodology
- Patient recruitment strategies
- Health psychology
Background:
- Participant recruitment is a significant challenge in clinical trials.
- Understanding patient willingness to participate is crucial for trial success.
Purpose of the Study:
- To develop and validate the Join Clinical Trial Questionnaire (JoinCT).
- To explore factors influencing patients' willingness to join clinical trials.
Main Methods:
- A four-phase questionnaire development process.
- Field-testing using a cross-sectional survey of 389 cancer patients.
- Assessed content validity, internal consistency (Cronbach's alpha), and model fit (CFA).
Main Results:
- The JoinCT questionnaire was validated with excellent reliability and validity.
- Four key domains influencing willingness were identified: knowledge, perception of benefits, perception of risks, and confidence.
- The overall model fit of the JoinCT framework was excellent.
Conclusions:
- The validated JoinCT questionnaire is a reliable tool for assessing factors related to clinical trial participation.
- Knowledge, perceived benefits, perceived risks, and confidence are significant determinants of willingness to participate in clinical trials.
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