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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Timing of Postpartum Depressive Symptoms
Cheryl L Robbins1, Jean Y Ko1,2, Denise V D'Angelo1
1Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Many women develop postpartum depression later in the first year. Early screening for postpartum depression (PPD) is crucial, as nearly 3 in 5 women with PPD at 9-10 months did not report symptoms earlier.
Area of Science:
- Reproductive Health
- Maternal Mental Health
- Public Health
Background:
- Postpartum depression (PPD) significantly impacts maternal-child interactions.
- Research on PPD symptoms in the later postpartum period (9-10 months) is limited.
Purpose of the Study:
- To estimate the prevalence of PPD symptoms at 9-10 months postpartum.
- To identify factors associated with PPD at 9-10 months.
- To examine PPD prevalence across early and later postpartum periods.
Main Methods:
- Analysis of 2019 Pregnancy Risk Assessment Monitoring System (PRAMS) data linked with a telephone follow-up survey.
- Study included 1,954 women across 7 states, assessed at 9-10 months postpartum.
- Prevalence ratios were used to examine associations with PPD symptoms.
Main Results:
- The prevalence of PPD symptoms at 9-10 months was 7.2%.
- Over half (57.4%) of women with PPD at 9-10 months had no prior symptoms.
- PPD at 9-10 months was linked to Medicaid insurance, prior depression, and current anxiety.
Conclusions:
- A significant proportion of women develop PPD later in the postpartum period.
- Continuous screening for depression throughout the first year is recommended.
- Identifying women with delayed PPD onset is critical for timely intervention.
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