Related Experiment Video
Updated: Jul 11, 2025

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
Electroconvulsive therapy for obsessive compulsive symptoms in a patient with schizophrenia: a brief report
Chih-Yuan Lin1, Hsin-Ya Kuo2, Cheng-Ho Chang2
1Department of Psychiatry, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.
Abstract:
Comorbid obsessive-compulsive disorder (OCD) is common among patients with schizophrenia. The role of electroconvulsive therapy (ECT) in the treatment of OCD in schizophrenia is unclear. Herein, we present a 45-year-old man who was diagnosed with schizophrenia along with OCD and received ECT due to relapse of psychosis owing to refractive schizophrenia. Together with psychotic symptoms, obvious symptoms of OCD were observed prior to treatment, including obsessive thoughts, difficulty in starting activities, and repetitive and ritualistic behavior. After 12 sessions of ECT, symptoms of schizophrenia and OCD both improved significantly (Positive and Negative Syndrome Scale [PANSS] score decreased from 95 points to 58 points, and Yale - Brown Obsessive-Compulsive Scale [Y-BOCS] score decreased from 29 points to 11 points). Mild aggravation of OCD symptoms was noted 3 months after ECT treatment (Y-BOCS score increased from 11 points to 17 points) without obvious relapse of psychotic symptoms (PANSS score changed from 58 points to 62 points). In conclusion, ECT could be considered as an alternative therapy for patients with schizophrenia and OCD with limited response to pharmacological treatment.
Related Concept Videos
Electroconvulsive Therapy
Obsessive-Compulsive Disorder
Psychosurgery
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Operant Conditioning Intervention
In operant conditioning, behaviors that are...
Mania and Antimanic Drugs: Overview
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

