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Related Experiment Video

Updated: Jul 11, 2025

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
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Association of e-Cigarette Use and Postpartum Depression: Pregnancy Risk Assessment Monitoring System 2016-2019.

Briana M Choi1, Andrea H Weinberger2,3, Nicole Petersen4

  • 1Center for Health Outcomes and PharmacoEconomic Research, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona, USA.

Journal of Women'S Health (2002)
|November 9, 2023
PubMed
Summary
This summary is machine-generated.

Electronic cigarette use is not an independent risk factor for postpartum depression (PPD). However, it may indicate a higher risk, warranting further research into its impact on maternal mental health.

Keywords:
PRAMSdepressione-cigarettesperinatalpostpartumpregnancy

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Area of Science:

  • Public Health
  • Reproductive Health
  • Mental Health

Background:

  • Postpartum depression (PPD) is a significant public health issue.
  • While combustible cigarette use is linked to PPD, the association with electronic cigarette (e-cigarette) use remains unclear.
  • Previous research suggests e-cigarette use during pregnancy may increase depressive symptoms.

Purpose of the Study:

  • To investigate the relationship between e-cigarette use and the risk of developing PPD.
  • To determine if e-cigarette use is an independent risk factor for PPD.

Main Methods:

  • Analysis of Pregnancy Risk Assessment Monitoring System (PRAMS) data from 2016-2019.
  • Retrospective self-report of e-cigarette use (any vs. none) in the past 2 years, pre-pregnancy, and during pregnancy.
  • Logistic regression analyses, including adjusted models controlling for covariates like age, race, ethnicity, and other substance use.

Main Results:

  • Unadjusted analyses showed a statistically significant association between past 2-year e-cigarette use and PPD (OR: 1.63).
  • Excluding users of combustible cigarettes and/or hookah, past 2-year e-cigarette use remained significantly associated with PPD (OR: 1.78).
  • No adjusted analyses demonstrated a statistically significant association between e-cigarette use and PPD.

Conclusions:

  • E-cigarette use, in itself, does not appear to be an independent risk factor for PPD.
  • E-cigarette use might serve as a clinical marker for increased PPD risk.
  • Further research is needed to fully understand the impact of e-cigarette use on PPD.