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Putting the pieces together: Chimeric virus strategy decode Dengue virus 3 antibody responses
1Department of Infection Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Abstract:
In this issue of Cell Host & Microbe, Munt et al. shed light on variability in human immune responses after natural infection compared to vaccination by using a recombinant virus platform that expresses chimeric Dengue virus type 1 and type 3 envelope proteins to identify and characterize type-specific neutralizing antibodies.
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