Dual-functional molecularly imprinted doped carbon dot based on metal-organic frameworks for tetracycline adsorption
Qingyan Bai1, Hongwei Wang1, Yunjia Xu1
1School of Chemistry and Chemical Engineering, Key Laboratory for Chemical Engineering and Technology, State Ethnic Affairs Commission, Ningxia Key Laboratory of Solar Chemical Conversion Technology, North Minzu University, Yinchuan, 750021, China.
Abstract:
A carbon dot (CD) was prepared by using tryptophan as a single carbon source and demonstrated its good selective fluorescence quenching effect on tetracycline (TC). The modified metal-organic frameworks (MOF) NH2-MIL-101 was chosen as matrix, doped with CD, molecularly imprinted polymer (MIP) prepared with TC as the template, and finally CD-MOF-MIP complexes (CD@MIP) was synthesized. For comparison, MIP were also prepared without CD as well as non-imprinted polymers and their ability was tested, respectively. CD@MIP is a nanomaterial with bright fluorescence under the irradiation of ordinary UV equipment (λ = 360 nm), which has a fast and stable fluorescence quenching for TC and a good linear relationship for TC in the concentration range 0-400 μmol L-1. The quantum yield of CD@MIP was 12.75% and the 3σ limit of detection (LOD) for CD@MIP was 0.59 μmol L-1. The maximum adsorption capacity of CD@MIP reached 304.6 mg g-1 and the adsorption equilibrium was reached after about 75 min. The adsorption of CD@MIP to tetracycline spiked in milk samples reached 90.0 mg g-1 within 2 h, which was much higher than that of NIP (48.4 mg g-1) under the same conditions, as demonstrated by high performance liquid chromatography (HPLC). The results obtained showed that CD@MIP combined the high adsorption capacity of MOF, the specific adsorption of molecular imprinting and the fluorescence properties of CD, can determine and rapidly removeTC in the environment.
