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Solid-State NMR Spectroscopy to Probe State and Phase Transitions in Frozen Solutions

Yong Du1, Jinghan Li2, Wei Xu1

  • 1Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.

Molecular Pharmaceutics
|November 10, 2023
PubMed
Abstract

Keywords:
biopharmaceuticalchemical shiftscrystallizationfreeze concentratefrozen solutionhistidinepHsolid-state NMRsynchrotron X-ray diffractometry

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