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Related Experiment Videos

Cerebellar structure and function in the murine mutant "jolting".

D J Dick, R J Boakes, J M Candy

    Journal of the Neurological Sciences
    |December 1, 1986
    PubMed
    Summary

    The "jolting" mouse model exhibits Purkinje cell loss and axonal spheroids, leading to cerebellar ataxia. These neurological deficits are evident early in development, impacting motor function.

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    Myxoedema coma.

    Irish journal of medical science·2016

    Area of Science:

    • Neuroscience
    • Genetics
    • Cell Biology

    Background:

    • The cerebellum plays a crucial role in motor control and coordination.
    • Cerebellar ataxia is a debilitating neurological disorder characterized by a loss of voluntary coordination of muscle movements.

    Purpose of the Study:

    • To investigate the morphological and electrophysiological abnormalities in the cerebellum of the

    Main Methods:

    • Morphological analysis of cerebellar cortex in

    Main Results:

    • Significant Purkinje cell loss and axonal spheroids observed in adult

    Conclusions:

    • The

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