Deoxygenative Hydroboration of Aromatic Nitro Compounds Catalyzed by Tetra(diisopropylamido) Rare-Earth Metal-Lithium
Chuanling Chen1, Chengrong Lu1, Bei Zhao1
1Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, People's Republic of China.
Abstract:
The first example of the reduction of a nitro compound with HBPin catalyzed by tetra(diisopropylamido) rare-earth metal-lithium bimetallic complexes LiRE(NPr2)4(THF) (RE = La, Nd, Sm, Gd, and Y) was disclosed. A series of aromatic nitro compounds were reduced to N-borylamines in high yields (up to 99%). The derivatives of N-borylamines─amides and carbamates─were obtained in a sequential one-pot manner. Furthermore, kinetic studies of the deoxygenative hydroboration of nitro compounds were carried out.
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