Related Experiment Video

Updated: Jul 11, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.1K

Outcomes of left-sided heart valve surgery after heart transplantation: a systematic review

Besart Cuko1, Massimo Baudo2,3, Olivier Busuttil4

  • 1Department of Cardiology and Cardio-Vascular Surgery, Hopital Cardiologique de Haut-Leveque, Bordeaux University Hospital, Av. Magellan, Pessac, 33604, France. drcukobesart@gmail.com.

Heart Failure Reviews
|November 11, 2023
PubMed

Insights

Redo cardiac surgery for aortic or mitral valve disease after heart transplantation (HTx) is feasible. This systematic review shows positive outcomes in carefully selected patients, improving survival and potentially reducing re-transplantation needs.

Area of Science:

  • Cardiovascular Surgery
  • Transplantation Medicine
  • Cardiac Pathology

Background:

  • Improving survival post-heart transplantation (HTx) leads to increased incidence of late cardiac pathologies, particularly valvular disease.
  • Current clinical guidelines for redo cardiac surgery after HTx are lacking, creating a management gap for these complex patients.

Approach:

  • A systematic review was performed on adult patients undergoing surgical management for severe aortic and/or mitral valve disease post-heart transplantation.
  • Studies were included if they reported on left heart valve surgery, excluding concomitant valve surgery during HTx, transcatheter interventions, and heterotopic HTx.

Key Points:

  • The review analyzed 35 studies involving 44 mitral and 20 aortic valve surgery patients, with a mean time from HTx to reintervention of 6.19 years.
  • Post-reintervention survival rates were 65.6% for mitral valve surgery and 86.7% for aortic valve surgery after a mean follow-up of 2.78 and 1.53 years, respectively.
  • These interventions can improve functional status and survival, potentially decreasing the demand for donor hearts.

Conclusions:

  • Left-sided valvular cardiac reinterventions after heart transplantation represent a viable therapeutic option for carefully selected patients.
  • Despite positive findings, the need for more robust data to support these interventions is emphasized.
  • Addressing valvular disease post-HTx may enhance long-term outcomes and mitigate donor heart scarcity.

Keywords:
Aortic valveCardiac surgeryHeart transplantationMitral valveSystematic review

More Related Videos

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

379
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.4K

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
15
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
24
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
14
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
12
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
15