Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Vaccinations

Vaccinations

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Surveillance of catheter-associated urinary tract infections at an Australian tertiary hospital, 2024-2025.

Infection, disease & health·2026

Same author

Notes from the Field: Initial Public Health Response to a Measles Outbreak in a Close-Knit West Texas Community - January-February 2025.

MMWR. Morbidity and mortality weekly report·2026

Same author

Effectiveness of oral care for the prevention of non-ventilator hospital-acquired pneumonia (HAPPEN): a multicentre, stepped-wedge, cluster-randomised trial in Australia.

The Lancet. Infectious diseases·2026

Same author

Room-return ventilation and N95 respirator policies for reducing airborne pathogen exposure on hospital wards.

The Journal of hospital infection·2026

Same author

Global trends in norovirus genotype distribution among medically attended children with acute gastroenteritis, 2020-2025.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026

Same author

Culturally responsive nutrition interventions addressing chronic conditions in Latino adults living in the United States: a scoping review.

BMC nutrition·2026

Search research articles

Related Experiment Video

Updated: Jul 11, 2025

Quantifying Human Norovirus Virus-like Particles Binding to Commensal Bacteria Using Flow Cytometry

Quantifying Human Norovirus Virus-like Particles Binding to Commensal Bacteria Using Flow Cytometry

Published on: April 29, 2020

Vaccine value profile for norovirus.

George Armah¹, Ben A Lopman², Jan Vinjé³

¹Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana.

|November 11, 2023

Summary

Norovirus causes significant diarrheal disease and deaths globally, necessitating vaccine development. Current vaccine research shows promise but requires deeper understanding of viral mechanisms for effective control.

Keywords:

Global Health Policy Vaccine value Vaccines

More Related Videos

Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity

Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity

Published on: November 16, 2017

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. Part III. Virus Detection by RT-qPCR

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. Part III. Virus Detection by RT-qPCR

Published on: January 16, 2016

Related Experiment Videos

Last Updated: Jul 11, 2025

Quantifying Human Norovirus Virus-like Particles Binding to Commensal Bacteria Using Flow Cytometry

Quantifying Human Norovirus Virus-like Particles Binding to Commensal Bacteria Using Flow Cytometry

Published on: April 29, 2020

Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity

Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity

Published on: November 16, 2017

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. Part III. Virus Detection by RT-qPCR

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. Part III. Virus Detection by RT-qPCR

Published on: January 16, 2016

Area of Science:

Public Health
Virology
Vaccinology

Background:

Norovirus is a leading cause of diarrheal disease and mortality worldwide, particularly in children.
Despite improvements in hygiene, norovirus outbreaks persist globally, underscoring the need for effective interventions.
Existing norovirus vaccine development shows promise with diverse approaches, including VLP-based platforms.

Purpose of the Study:

To summarize the global impact of norovirus and the status of vaccine development.
To identify key knowledge gaps hindering norovirus vaccine efficacy and control.

Main Methods:

Review of global norovirus epidemiology and disease burden.
Analysis of the current norovirus vaccine pipeline and technological approaches.
Identification of critical research areas for understanding norovirus pathogenesis.

Main Results:

Norovirus accounts for a substantial proportion of diarrheal disease and causes hundreds of thousands of deaths annually.
The norovirus vaccine pipeline is diverse but lacks depth, with some promising VLP-based technologies.
Significant gaps remain in understanding norovirus attachment, internalization, and disease induction mechanisms.

Conclusions:

Norovirus remains a major global health challenge, demanding novel control strategies beyond sanitation.
Advancements in norovirus vaccine development are encouraging but require further research into viral mechanisms.
Addressing knowledge gaps in viral-host interactions is crucial for developing effective norovirus vaccines.