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Updated: Jul 11, 2025
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Intracranial Air Absorption through Arachnoid Granulation: New Considerations from Transsphenoidal Surgery and
Shinji Naganawa1, Rintaro Ito1,2, Mariko Kawamura1
1Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
Abstract:
Postsurgery intracranial air usually diminishes, presumably merging with cerebrospinal fluid (CSF) and venous circulation. Our study presents two transsphenoidal surgery cases, highlighting potential air absorption by arachnoid granulation (AG)-an underexplored phenomenon. AG has long been deemed pivotal for CSF absorption, but recent perspectives suggest a significant role in waste clearance, neuroinflammation, and neuroimmunity. These cases may stimulate renewed research on the multifaceted role of AG in neurofluid dynamics and potentially elucidate further AG functions.
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