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Related Concept Videos

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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Related Experiment Video

Updated: Jul 11, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

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Thyroid Metastasis to the Colon.

Eliza B Lewine1, Zinal Patel1, Jacqueline Forman1

  • 1Department of Gastroenterology, New York University Langone Hospital Long Island, Mineola, NY.

ACG Case Reports Journal
|November 13, 2023
PubMed
Summary
This summary is machine-generated.

Metastatic colon cancer from a thyroid primary is rare. This case highlights the importance of colorectal cancer screening after thyroid cancer diagnosis and regular follow-up screening.

Keywords:
colon cancer screeningcolorectal carcinomathyroid cancer

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Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Colorectal cancers (CRC) are rarely caused by metastasis from other primary sites, with common origins including lung, breast, and prostate.
  • Metastasis to the colon from a thyroid primary neoplasm is exceptionally uncommon.

Observation:

  • A 76-year-old male patient with a history of papillary thyroid carcinoma presented with colon polyps.
  • Colonoscopic and histopathological examination revealed polyps consistent with metastatic carcinoma originating from his primary thyroid cancer.

Findings:

  • The patient's colon polyps were histologically confirmed as metastatic papillary thyroid carcinoma.
  • This case represents an exceedingly rare instance of thyroid cancer metastasizing to the colon.

Implications:

  • The findings suggest that patients with a history of thyroid cancer should undergo prompt and regular colorectal cancer screening.
  • Early detection through screening may improve outcomes for patients with rare metastatic presentations of thyroid cancer.