[Distribution pattern of fibronectin in human lung cancer tissue]

The distribution pattern of fibronectin in human lung cancer tissues has been studied using the indirect immunoperoxidase technique. In adenocarcinoma fibronectin is observed in the basal side of cancer cells and tumor stroma. In squamous cell carcinoma, it is seen in the basal side of cancer cells, surface of cancer cells and tumor stroma. The difference between adenocarcinoma and squamous cell carcinoma in invasion and metastasis was investigated to have some relation to the distribution pattern of fibronectin.