Related Experiment Video
Updated: Jul 11, 2025
07:56
Protocol for Long Duration Whole Body Hyperthermia in Mice
Published on: August 25, 2012
11.6K
The Curie temperature: a key playmaker in self-regulated temperature hyperthermia.
Gopal Niraula1, Chengwei Wu2, Xiaogang Yu2
1Department of Physics, Federal University of Maranhão, São Luís, 65080-805, Brazil. surender76@gmail.com.
Journal of Materials Chemistry. B
|November 13, 2023
Summary
The Curie temperature of magnetic nanoparticles (MNPs) is crucial for self-control-temperature (SCT) magnetic induction hyperthermia (MIH). This property enables precise temperature control for effective cancer tumor treatment in biomedical applications.
Area of Science:
- Materials Science
- Physics
- Biomedical Engineering
Background:
- The Curie temperature defines the phase transition in magnetic materials from ferromagnetic to paramagnetic states.
- Self-control-temperature (SCT) using magnetic nanoparticles (MNPs) enables advanced applications, particularly in medicine.
- Magnetic induction hyperthermia (MIH) leverages MNPs for targeted cancer therapy.
Purpose of the Study:
- To provide a comprehensive review of the Curie temperature in magnetic materials.
- To explore the role of Curie temperature in SCT-based MIH for cancer treatment.
- To discuss factors influencing Curie temperature and MNP properties for clinical translation.
Main Methods:
- Review of fundamental magnetism and Curie's law.
- Analysis of theoretical predictions and experimental measurements of Curie temperature.
- Discussion on material evolution (alloys to ferrites) and particle property impacts (shape, size, concentration).
Main Results:
- Curie temperature acts as a critical switch for automatic temperature control in MIH.
- Biocompatibility and Curie temperature are key parameters for MNPs in clinical MIH.
- Particle characteristics significantly influence Curie temperature and thermal efficiency for tumor destruction.
Conclusions:
- SCT-based MIH shows promise for cancer therapy, with Curie temperature being a vital control factor.
- Optimizing MNP properties, including Curie temperature and biocompatibility, is essential for successful clinical application.
- Further research and development are needed to overcome challenges and advance SCT-based MIH towards clinical use.
More Related Videos
13:41Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
Published on: January 13, 2023
2.4K
06:43Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
24.3K
Related Concept Videos
01:25Increased Body Temperature
685
A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
685
01:19Homeostatic Imbalances in Body Temperature
133
Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
133
01:25Body Temperature
972
The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
972
01:26Thermoregulation
1.0K
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
1.0K
01:28Factors Affecting Body Temperature
4.3K
As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may include:
Factors may include:
4.3K
01:29Decreased Body Temperature
624
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
624