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Associations between physical inactivity and dementia prevalence: ecological study using global data
P Lloyd-Hazlegreaves1, L Hayes1, M S Pearce1
1Population Health Sciences Institute, Newcastle University, UK.
Public Health
|November 13, 2023
Summary
Physical inactivity is linked to higher dementia rates globally, with the association strengthening over time and being more pronounced in men. Public health initiatives promoting physical activity are crucial for dementia prevention.
Area of Science:
- Global health
- Epidemiology
- Neurology
Background:
- Dementia prevalence is rising globally.
- Physical inactivity (PI) is a modifiable lifestyle risk factor.
- Understanding the link between PI and dementia is a public health priority.
Purpose of the Study:
- To investigate the association between physical inactivity and dementia prevalence worldwide.
- To analyze how this relationship varies by sex, region, and income level.
Main Methods:
- Ecological study utilizing global data from 192 countries for 2010 and 2016.
- Analysis of age-standardized prevalence data for PI and dementia from WHO and Global Burden of Disease Study.
- Linear regression and stratified analyses to explore relationships and subgroup differences.
Main Results:
- A significant positive association was found between PI and dementia prevalence in both 2010 and 2016.
- The association was stronger in men than in women.
- Both dementia and PI prevalence increased with higher World Bank income groups.
Conclusions:
- Global data indicate a growing positive relationship between physical inactivity and dementia prevalence.
- The link between inactivity and dementia is stronger in men.
- Global public health interventions are needed to increase adherence to physical activity guidelines and mitigate dementia risk.
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