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Related Concept Videos

Structures of the Endocrine System00:59

Structures of the Endocrine System

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The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
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The Endocrine System01:29

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The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
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Adrenal Gland Disorders01:27

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Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
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An Overview of the Endocrine System01:10

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The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
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Regulation of Hormone Secretion01:19

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Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
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What is the Endocrine System?00:46

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The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
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Canine Intestinal Organoids in a Dual-Chamber Permeable Support System
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[Polyendocrine syndromes in dogs].

Sina Strey1, Reinhard Mischke1, Johanna Rieder1

  • 1Klinik für Kleintiere, Stiftung Tierärztliche Hochschule Hannover, Hannover.

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|November 13, 2023
PubMed
Summary

Autoimmune polyendocrine syndrome (APS) is a rare combination of endocrine diseases in dogs. Early recognition and diagnosis of additional endocrinopathies are crucial for effective treatment and management.

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Area of Science:

  • Veterinary Endocrinology
  • Immunology in companion animals

Context:

  • Autoimmune polyendocrine syndrome (APS) is a rare condition in dogs.
  • Common APS combinations include hypoadrenocorticism with hypothyroidism, and diabetes mellitus.
  • Less frequent combinations involve hypoparathyroidism and orchitis.

Purpose:

  • To summarize canine autoimmune polyendocrine syndrome cases.
  • To highlight diagnostic and therapeutic considerations for APS in dogs.
  • To review literature and own hospital cases of canine APS.

Summary:

  • APS involves multiple autoimmune endocrine disorders, rarely seen in dogs.
  • Diagnosis requires identifying individual endocrinopathies and hormone replacement therapy.
  • New clinical signs in treated dogs may indicate developing or misdiagnosed endocrinopathies.

Impact:

  • Improves understanding of rare endocrine diseases in veterinary medicine.
  • Guides clinicians in diagnosing and managing complex endocrine cases in dogs.
  • Enhances long-term patient care through comprehensive endocrine assessment.