Related Experiment Video
Updated: Jul 11, 2025

Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics
Published on: December 1, 2023
On inverse problems for several coupled PDE systems arising in mathematical biology
Ming-Hui Ding1, Hongyu Liu2, Guang-Hui Zheng3
1Department of Mathematics, City University of Hong Kong, Kowloon, Hong Kong, China.
Abstract:
In this paper, we propose and study several inverse problems of identifying/determining unknown coefficients for a class of coupled PDE systems by measuring the average flux data on part of the underlying boundary. In these coupled systems, we mainly consider the non-negative solutions of the coupled equations, which are consistent with realistic settings in biology and ecology. There are several salient features of our inverse problem study: the drastic reduction of the measurement/observation data due to averaging effects, the nonlinear coupling of multiple equations, and the non-negative constraints on the solutions, which pose significant challenges to the inverse problems. We develop a new and effective scheme to tackle the inverse problems and achieve unique identifiability results by properly controlling the injection of different source terms to obtain multiple sets of mean flux data. The approach relies on certain monotonicity properties which are related to the intrinsic structures of the coupled PDE system. We also connect our study to biological applications of practical interest.
Related Concept Videos
Couette Flow
Poisson's And Laplace's Equation
Second Order systems II
Relation between Mathematical Equations and Block Diagrams
Linear Approximation in Time Domain
For a simple pendulum with a mass evenly distributed along its length and the center of mass located at half the pendulum's length,...
The Power Flow Problem and Solution

