Related Experiment Video
Updated: Jul 11, 2025

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
Published on: January 17, 2025
Improving the Therapeutic Relationship When Prescribing Antidepressants: A Pilot Study
Konrad Michel1, Daniela Lutz-Beck2, Sylva Engeroff3
1University Hospital of Psychiatry, University of Bern, CH-3008 Bern, Switzerland.
A new manual for psychiatrists improved patient satisfaction with the doctor-patient relationship during antidepressant treatment. This intervention also increased antidepressant medication adherence over six months.
Area of Science:
- Psychiatry
- Clinical Psychology
- Pharmacotherapy
Background:
- The doctor-patient relationship quality influences pharmacotherapy outcomes in depression.
- Enhancing therapeutic relationships is crucial for effective depression treatment.
Purpose of the Study:
- To develop and pilot a manual to improve the doctor-patient relationship in depression pharmacotherapy.
- To assess the impact of the manual on patient satisfaction and treatment adherence.
Main Methods:
- A pilot study compared a manual-guided approach with usual care for depression pharmacotherapy.
- Patient-centered treatment parameters and satisfaction were assessed at three and six months.
- The intervention focused on enhancing the doctor-patient interaction, not medication choice.
Main Results:
- Patient satisfaction with the doctor-patient relationship significantly increased in the manual group at three months.
- Antidepressant medication continuation at six months was higher in the manual group.
- Depression parameters improved similarly in both groups, with no significant differences.
Conclusions:
- A brief intervention using written materials for doctors prescribing antidepressants can enhance patient and doctor satisfaction.
- The manual shows potential for improving adherence to antidepressant medication.
- Further research is warranted to confirm these findings in larger populations.
Related Concept Videos
Antidepressant Drugs: Overview
Antidepressant Drugs: MAOIs and Other Agents
Elements Crucial for Effective Psychotherapy
The Therapeutic Alliance
The therapeutic alliance refers to the relationship between the therapist and the client. The alliance strengthens when the therapist and the client engage in a nurturing, supportive, trusting, empathetic, and respectful relationship, improving therapeutic outcomes. Therapists must monitor this relationship...
The Placebo Effect
Drug Therapy
Antianxiety Medications
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs

