Monoterpene Thiols: Synthesis and Modifications for Obtaining Biologically Active Substances

Area of Science:

• Organic Chemistry
• Natural Products Chemistry
• Polymer Science

Background:

• Monoterpene thiols are key natural flavor compounds found in citrus, grapes, and currants.
• They are utilized in the food and perfume industries as flavoring agents.
• Synthetic applications include asymmetric synthesis, catalysis, and emerging green polymer development.

Purpose of the Study:

• To review synthesis methods for various monoterpene thiol structures.
• To explore the applications of monoterpene thiols and their derivatives.
• To highlight their potential in creating antimicrobial compounds.

Main Methods:

• Review of synthetic methodologies for acyclic, mono-, and bicyclic monoterpene thiols.
• Analysis of literature on the applications of these compounds.
• Examination of studies investigating antimicrobial properties.

Main Results:

• Established synthetic routes for diverse monoterpene thiol structures.
• Identified applications in flavoring, chiral synthesis, catalysis, and polymer science.
• Demonstrated potential for developing compounds with antimicrobial activity.

Conclusions:

• Monoterpene thiols are versatile compounds with broad applications.
• Their synthesis and derivatization offer opportunities for novel materials and pharmaceuticals.
• Further research into their antimicrobial potential is warranted.