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CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention (PCI) in the Million

Catherine Chanfreau-Coffinier1, Kevin A Friede2, Mary E Plomondon3

  • 1VA Salt Lake City Heath Care System, Salt Lake City, UT.

Medrxiv : the Preprint Server for Health Sciences
|November 14, 2023
PubMed
Summary

CYP2C19 loss-of-function alleles increase MACE risk in acute coronary syndrome patients after PCI. However, CYP2C19 genotype does not impact MACE risk in stable ischemic heart disease patients treated with clopidogrel.

Keywords:
CYP2C19 genotypeacute coronary syndromeclopidogrelpercutaneous coronary interventionstable ischemic heart disease

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