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Updated: Jul 11, 2025

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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Learning gene networks under SNP perturbation using SNP and allele-specific expression data

Jun Ho Yoon1, Seyoung Kim1

  • 1Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA 15213, United States of America.

Biorxiv : the Preprint Server for Biology
|November 14, 2023
PubMed
Summary

We developed CiTruss, a new method to reconstruct gene networks by analyzing genetic variants (eQTLs) that affect gene expression. This approach reveals local and global network structures, offering insights into gene regulation and genetic diversity.

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