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Updated: Jul 11, 2025

Tracking Morphogenetic Tissue Deformations in the Early Chick Embryo
Published on: October 17, 2011
Growth couples temporal and spatial fluctuations of tissue properties during morphogenesis
Antoine Fruleux1, Lilan Hong2, Adrienne H K Roeder3
1RDP, Université de Lyon, ENS de Lyon, UCB Lyon 1, INRAE, CNRS, 69364 Lyon Cedex 07, France LadHyX, CNRS, Ecole polytechnique, Institut Polytechnique de Paris, 91128 Palaiseau Cedex, France and LPTMS, CNRS, Université Paris-Saclay, 91405, Orsay, France.
Living tissues exhibit fluctuations that are coupled by growth, revealing long-range correlations in spatial and temporal variations. This growth mechanism, termed "fluctuation stretching," impacts tissue development and robustness.
Area of Science:
- * Developmental Biology
- * Biophysics
- * Quantitative Biology
Background:
- * Living tissues exhibit spatiotemporal fluctuations at multiple scales, potentially involved in sensing tissue state or size.
- * Theoretical models predict long-range correlations in growth fluctuations within developing tissues.
- * Understanding these fluctuations is key to comprehending tissue morphogenesis and robustness.
Conclusions:
- * Growth intrinsically couples temporal and spatial fluctuations, impacting morphogenesis.
- * Kinematic constraints on spatiotemporal fluctuations are crucial for the robustness of tissue development.
- * The findings provide a unifying framework for understanding tissue fluctuations across various conditions.
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