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Updated: Jul 11, 2025

Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry
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Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry

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Non-modular Fatty Acid Synthases Yield Unique Acylation in Ribosomal Peptides

Hengqian Ren, Chunshuai Huang, Yuwei Pan

    Biorxiv : the Preprint Server for Biology
    |November 14, 2023
    PubMed
    Summary

    Researchers discovered lipoavitides, novel RiPP/fatty acid hybrid lipopeptides. These molecules feature a unique HMP-modified N-terminus, expanding natural product diversity and offering tools for lipopeptide bioengineering.

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