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Updated: Jul 11, 2025

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Access and barriers to genomic classifiers for breast cancer and prostate cancer in India
Sruthi Ranganathan1, Edward Christopher Dee2, Neha Debnath3
1Department of Medicine, Cambridge University, Cambridge, UK.
Abstract:
The incidence of cancer in general, including breast and prostate cancer specifically, is increasing in India. Breast and prostate cancers have genomic classifiers developed to guide therapy decisions. However, these genomic classifiers are often inaccessible in India due to high cost. These classifiers may also be less suitable to the Indian population, as data primarily from patients in wealthy Western countries were used in developing these genomic classifiers. In addition to the limitations in using these existing genomic classifiers, developing and validating new genomic classifiers for breast and prostate cancer in India is challenging due to the heterogeneity in the Indian population. However, there are steps that can be taken to address the various barriers that currently exist for accurate, accessible genomic classifiers for cancer in India.
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