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Overview of Electron Microscopy01:25

Overview of Electron Microscopy

The wavelengths of visible light ultimately limit the maximum theoretical resolution of images created by light microscopes. Most light microscopes can only magnify 1000X, and a few can magnify up to 1500X. Electrons, like electromagnetic radiation, can behave like waves, but with wavelengths of 0.005 nm, they produce significantly greater resolution up to 0.05 nm as compared to 500 nm for visible light. An electron microscope (EM) can create a sharp image that is magnified up to 2,000,000X.
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Light-driven micro/nanomotors in biomedical applications.

Xuejiao Zeng1,2,3, Mingzhu Yang1,2,3, Hua Liu1,2,3

  • 1School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China. huyr@zzu.edu.cn.

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|November 14, 2023
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Summary
This summary is machine-generated.

Light-driven micro/nanomotors (MNMs) offer a promising solution for targeted drug delivery, overcoming biological barriers for improved therapeutic efficiency in various diseases. This review highlights their potential for clinical applications.

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Drug Delivery Systems

Background:

  • Current passive drug delivery systems exhibit limited therapeutic efficiency.
  • Micro/nanomotors (MNMs) have emerged as a significant area of research in biomedicine.
  • Light-driven MNMs present advantages like reversibility, control, and efficiency over other methods.

Purpose of the Study:

  • To review the classification and mechanisms of light-driven MNMs.
  • To highlight recent applications of light-driven MNMs in overcoming biological barriers.
  • To discuss future prospects and challenges for clinical translation.

Main Methods:

  • Literature review focusing on light-driven micro/nanomotors.
  • Analysis of mechanisms for overcoming physiological and pathological barriers.
  • Synthesis of recent advancements in the last five years.

Main Results:

  • Light-driven MNMs demonstrate potential in treating tumors, and gastrointestinal, cardiovascular, and cerebrovascular diseases.
  • These nanomotors can effectively navigate and overcome biological barriers in vivo.
  • Recent research showcases diverse applications in targeted therapies.

Conclusions:

  • Light-driven MNMs hold significant promise for advancing targeted drug delivery.
  • Overcoming biological barriers in vivo is a key area of development.
  • Further research is needed to address challenges and promote clinical application.