Related Experiment Video
Updated: Jul 11, 2025

Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
Assessing the severity of medication administration errors identified in an observational study using a valid and
Lindemberg Assunção-Costa1, Charleston Ribeiro Pinto2, Juliana Ferreira Fernandes Machado3
1Department of Medicine, School of Pharmacy, Federal University of Bahia and National Institute for Phamaceutical Assistence and Pharmacoeconomy - INAFF, Rua Barão de Jeremoabo, 147, 2º andar, Campus Ondina, Salvador, Bahia, 40170-115, Brazil. lindemberg.rn@gmail.com.
This study assessed medication errors in a teaching hospital, finding most were moderate. However, the rate of potentially serious medication errors was higher than in prior research, indicating a need for improved safety strategies.
Area of Science:
- Healthcare Quality and Safety
- Clinical Pharmacy
- Patient Safety Research
Background:
- Limited epidemiological data exists on the severity of medication errors.
- Standardization in identifying medication administration errors and appropriate severity assessment tools are lacking.
- This study addresses the need to evaluate potential error severity using direct observation in a teaching hospital.
Purpose of the Study:
- To assess the potential severity of medication administration errors identified through direct observation.
- To provide a quantitative measure of error severity using a validated scoring system.
- To identify patterns in potentially serious medication errors.
Main Methods:
- A validated 10-point scale was used to assess the potential severity of medication administration errors.
- 203 previously identified errors were categorized into 67 unique error types.
- A panel of physicians, nurses, and pharmacists evaluated the severity of each error type.
Main Results:
- 8.8% of errors were classified as minor, 82.8% as moderate, and 8.4% as severe.
- Technical errors constituted 41% of potentially serious errors.
- Insulin was frequently involved in potentially serious errors, with 53% of these involving intravenous administration.
Conclusions:
- The expert panel deemed most medication errors to be of moderate potential severity.
- The observed frequency of potentially serious medication errors exceeded that of previous studies using similar methods.
- There is a clear need to implement strategies to decrease the occurrence of serious medication errors.
Related Concept Videos
Systematic Error: Methodological and Sampling Errors
Sampling errors originate from improper sampling methods or the wrong sample population. These errors can be minimized by refining the sampling strategy. Defective instruments or faulty calibrations are the sources of instrumental...
Errors occurring during blood pressure monitoring
Several factors...
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Random and Systematic Errors
Blind Procedures

