Clock gene Per3 deficiency disrupts circadian alterations of gut microbiota in mice

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In Vitro Bioluminescence Assay to Characterize Circadian Rhythm in Mammary Epithelial Cells
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Published on: September 28, 2017

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Xiaoxian Xie1,2,3, Haoshen Xu1, Ruonan Shu1

  • 1College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.

Acta Biochimica Et Biophysica Sinica
|November 15, 2023
PubMed
Abstract

No abstract available in PubMed .

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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