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Carpal bone replacement using personalized 3D printed tantalum prosthesis.

Changgui Zhang1, Hao Chen1, Huaquan Fan1

  • 1Center for Joint Surgery, Southwest Hospital, Army Medical University, Chongqing, China.

Frontiers in Bioengineering and Biotechnology
|November 15, 2023
PubMed
Summary
This summary is machine-generated.

Three-dimensional (3D) printed tantalum prostheses offer a promising solution for carpal osteonecrosis, restoring wrist function and strength comparable to the healthy contralateral side. This innovative approach significantly reduces pain and improves range of motion, demonstrating the potential of personalized implants.

Keywords:
3D printingcarpal bone replacementpersonalizedtantalum metalwrist

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Area of Science:

  • Orthopedic Surgery
  • Biomaterials Engineering
  • 3D Printing Technology

Background:

  • Scaphoid and lunate fractures are common, with traditional treatments for carpal osteonecrosis leading to complications.
  • Carpal bone replacement using patient-specific implants is an emerging alternative.
  • Three-dimensional (3D) printed tantalum offers excellent biocompatibility and anatomical customization.

Purpose of the Study:

  • To evaluate carpal function and prosthesis-related outcomes after carpal bone replacement with 3D printed tantalum prostheses.
  • To assess the efficacy of this novel treatment for carpal osteonecrosis.

Main Methods:

  • Seven patients with carpal osteonecrosis underwent carpal bone replacement using 3D printed tantalum prostheses.
  • Preoperative and postoperative wrist function were assessed using DASH, Mayo Wrist Scores, and Visual Analog Scale (VAS) for pain.
  • Range of motion (ROM), grip strength, and pinch strength were measured; radiographs evaluated prosthesis stability.

Main Results:

  • Follow-up averaged 19.6 months; operated wrists showed no significant difference in grip/pinch strength or ROM compared to the contralateral side.
  • Significant improvements were observed in VAS, DASH, and Mayo Wrist Scores post-surgery, indicating reduced pain and enhanced function.
  • All tantalum prostheses remained stable without complications.

Conclusions:

  • 3D printed tantalum prostheses are effective for carpal bone replacement, restoring function and stability in patients with carpal osteonecrosis.
  • This technology holds potential for personalized treatment of complex anatomical structures and irregular bone defects beyond the wrist.
  • 3D printed tantalum represents a significant advancement in personalized medicine and precise orthopedic interventions.