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Updated: Jul 11, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

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Evidence from a meta-analysis and systematic review reveals the global prevalence of mild cognitive impairment

Wen-Xin Song1, Wei-Wei Wu1, Yuan-Yuan Zhao1

  • 1The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.

Frontiers in Aging Neuroscience
|November 15, 2023
PubMed
Abstract

Insights

The global prevalence of mild cognitive impairment (MCI) is 19.7%. MCI rates significantly increased after 2019, particularly in hospitals, possibly due to COVID-19.

Area of Science:

  • Gerontology and Public Health
  • Neuroscience and Epidemiology

Background:

  • Mild cognitive impairment (MCI) represents a critical transitional phase between normal aging and dementia, necessitating accurate prevalence data.
  • Understanding the global epidemiology of MCI is vital for developing targeted interventions and healthcare strategies.

Approach:

  • A systematic meta-analysis was conducted, adhering to PRISMA 2020 guidelines, by searching multiple databases up to March 2023.
  • Data from 233 studies encompassing 676,974 individuals over 50 years old were analyzed using a random-effects model.
  • Quality assessment utilized the AHRQ methodology checklist, ensuring the reliability of the pooled prevalence estimates.

Key Points:

  • The pooled global prevalence of MCI among individuals over 50 years old was found to be 19.7%.
  • A significant increase in MCI prevalence was observed post-2019, with rates reaching 32.1%.
  • MCI prevalence was notably higher in hospital settings (34.0%) compared to nursing homes (22.6%) and communities (17.9%), especially following the COVID-19 pandemic.

Conclusions:

  • The global prevalence of MCI is 19.7%, influenced by survey year and sample source.
  • The surge in MCI prevalence post-2019, particularly in hospitals, is potentially linked to the COVID-19 pandemic.
  • Increased attention and resource allocation are crucial for populations at risk of MCI.
Keywords:
COVID-19global prevalencemeta-analysismild cognitive impairmentsystematic review

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