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Updated: Jul 11, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Kidney function assessment in the geriatric population
Abimereki Muzaale1, Adnan Khan2, Richard J Glassock3
1Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Kidney function naturally declines with age. However, chronic kidney disease (CKD) may be overdiagnosed in older adults without albuminuria, necessitating age-adapted definitions.
Area of Science:
- Nephrology
- Geriatric Medicine
- Renal Physiology
Background:
- Kidney function naturally declines with aging.
- This decline can be exacerbated by disease progression.
- Geriatric populations often present with frailty and comorbidities.
Conclusions:
- Age-related GFR decline is a normal physiological process.
- Current CKD definitions may lead to overdiagnosis and unnecessary referrals in the elderly.
- Age-adapted CKD definitions, particularly in the absence of albuminuria, are crucial for accurate diagnosis and management.
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