Related Experiment Video
Updated: Jul 11, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
Immune targets to stop future SARS-CoV-2 variants
Milena Silva Souza1,2, Jéssica Pires Farias1, Wilson Barros Luiz2
1Western Bahia Virology Institute, Center of Biological Sciences and Health, Federal University of Western Bahia , Barreiras, Bahia, Brazil.
Importance:
The emergence of SARS-CoV-2 had a major impact across the world. It is true that the collaboration of scientists from all over the world resulted in a rapid response against COVID-19, mainly with the development of vaccines against the disease. However, many viral genetic variants that threaten vaccines have emerged. Our study reveals highly conserved antigenic regions in the vaccines have emerged. Our study reveals highly conserved antigenic regions in the spike protein in all variants of concern (Alpha, Beta, Gamma, Delta, and Omicron) as well as in the wild-type virus. Such immune targets can be used to fight future SARS-CoV-2 variants.
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