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Updated: Jul 11, 2025

Enzyme-linked Immunospot Assay ELISPOT: Quantification of Th-1 Cellular Immune Responses Against Microbial Antigens
Published on: November 23, 2010
Performance evaluation of Espline HTLV-I/II, a newly developed rapid immunochromatographic antibody test for
Madoka Kuramitsu1, Haruka Momose1, Yuichiro Uchida2
1Research Center for Biological Products in the Next Generation, National Institute of Infectious Diseases , Tokyo, Japan.
Importance:
The World Health Organization estimated that 5-10 million people are infected with human T-cell leukemia virus type 1 (HTLV-1). This number is likely to be underestimated because reliable endemic data are available for only approximately 1.5 billion people worldwide. The point-of-care test is a powerful tool for the easy and quick detection of infections without the requirement for expensive instruments and laboratory equipment. Espline HTLV-I/II, a newly developed rapid immunochromatographic antibody test that was evaluated in this study, might significantly advance our understanding of the global epidemiology of HTLV-1 infection.

