[Methods, applications, and future perspectives of intraoperative tissue identification]

Sanja Hermanns1, Sascha Dammeier1, Alexander Neugebauer1

  • 1Erbe Elektromedizin GmbH, Waldhörnlestr. 17, 72072, Tübingen, Deutschland.

PubMed

Insights

New technologies enhance intraoperative tissue identification, aiding minimally invasive surgery and cancer treatment. Advancements include real-time AI tools for improved accuracy and reduced variability in surgical interventions.

Area of Science:

  • Biomedical Engineering
  • Surgical Technology
  • Medical Imaging

Context:

  • Technological advancements over the past century have focused on intraoperative tissue identification and differentiation.
  • Minimally invasive medicine relies on precise identification of target structures while preserving adjacent tissues.
  • Oncology benefits significantly from technologies that identify or classify neoplastic tissue, improving cancer surgery outcomes, such as in breast cancer operations.

Purpose:

  • To review and assess the utility and application of various technologies for intraoperative tissue identification.
  • To highlight the evolution from ex vivo to in situ and asynchronous to real-time clinical assistance.
  • To explore the integration of Artificial Intelligence (AI) in refining existing and developing new methods for enhanced surgical accuracy.

Summary:

  • Technologies leverage distinct physical tissue characteristics like induced fluorescence, optical coherence, and electrical impedance.
  • Recent developments emphasize real-time, in situ assistance, exemplified by optical emission spectroscopy.
  • Future refinements involve AI integration to boost performance and minimize inter-operator variability in surgical procedures.

Impact:

  • Improved surgical precision and patient outcomes through enhanced tissue differentiation.
  • Facilitation of minimally invasive surgical techniques with greater confidence.
  • Potential for AI-driven tools to standardize and elevate the quality of surgical interventions across different operators.

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