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Epidemiology of Invasive Meningococcal Disease in Colombia: A Retrospective Surveillance Database Analysis

Wilfrido Coronell-Rodriguez1, Diana C Caceres2, Otavio Cintra3

  • 1Faculty of Medicine, University of Cartagena, Serena del Mar Hospital, Cartagena, Colombia.

Infectious Diseases and Therapy
|November 15, 2023
PubMed
Abstract

Insights

Invasive meningococcal disease (IMD) incidence in Colombia is low but highest in infants. Serogroup C is now dominant, highlighting the need for targeted vaccination strategies.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • Invasive meningococcal disease (IMD) presents significant morbidity and mortality risks.
  • Understanding the epidemiology of IMD in Colombia is crucial for public health interventions.

Purpose of the Study:

  • To analyze the historical and current epidemiological trends of IMD in Colombia.
  • To identify high-risk populations and geographical distribution of IMD cases.

Main Methods:

  • Retrospective analysis of surveillance data from 1988 to 2021.
  • Data extraction from public reports and hospital records in Cartagena.

Main Results:

  • IMD incidence ranged from 0.04-0.18 per 100,000 between 2015-2021, with highest rates in infants (<1 year).
  • Serogroup C became dominant since 2015, followed by B and Y, shifting from the previous dominance of Serogroup B.
  • Cases concentrated in Bogotá and Antioquia; Cartagena showed higher lethality in poorer neighborhoods.

Conclusions:

  • IMD incidence is low overall but critical in infants.
  • Serogroup C, B, and Y are key targets for vaccination efforts.
  • Targeted vaccination strategies are recommended to align with global meningitis elimination goals.
Keywords:
ColombiaEpidemiologyMeningococcal infectionsNeisseria meningitidisSerogroup

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