Related Experiment Video

Updated: Jul 11, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

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Cardiac Resynchronization Therapy Using Single Site Left Ventricular Pacing in a Tricuspid Atresia Patient With Left

Shin Ono1, Jan Janoušek2, Takeshi Ikegawa1

  • 1Department of Pediatric Cardiology, Kanagawa Children's Medical Center, Yokohama, Japan.

CJC Pediatric and Congenital Heart Disease
|November 16, 2023
PubMed

Insights

Single-site cardiac resynchronization therapy (CRT) successfully enabled Fontan completion in a patient with tricuspid atresia and left bundle branch block. This approach shows promise for complex congenital heart disease patients.

Area of Science:

  • Cardiology
  • Congenital Heart Disease
  • Electrophysiology

Background:

  • Cardiac resynchronization therapy (CRT) typically involves biventricular pacing.
  • Left ventricular-only pacing is noninferior to biventricular pacing in specific patient groups.
  • Evidence for single-site pacing in single-ventricle physiology is lacking.

Observation:

  • A patient with tricuspid atresia and left bundle branch block underwent CRT.
  • Single-site pacing was utilized in this complex case.
  • The patient was undergoing preparation for Fontan completion.

Findings:

  • Successful Fontan completion was achieved with single-site CRT.
  • This demonstrates the feasibility of single-site pacing in this specific population.
  • The therapy was well-tolerated, facilitating the surgical procedure.

Implications:

  • Single-site CRT may be a viable option for patients with single-ventricle physiology and conduction abnormalities.
  • This approach could simplify management and improve outcomes in complex congenital heart disease.
  • Further research is warranted to explore the broader application of single-site CRT in similar cases.

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