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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
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Hepatobiliary tuberculosis in the developing world.
Ma Jenina Angela Esguerra-Paculan1, Jonathan Soldera2
1Acute Medicine, University of South Wales, Cardiff CF37 1DL, United Kingdom.
World Journal of Gastrointestinal Surgery
|November 16, 2023
Summary
Hepatobiliary tuberculosis presents diagnostic challenges. Early identification and treatment using standard anti-TB drugs improve patient outcomes, highlighting the need for accurate diagnosis and management.
Area of Science:
- Hepatology
- Infectious Diseases
- Radiology
Background:
- Hepatobiliary tuberculosis is difficult to diagnose due to overlapping symptoms with other liver conditions.
- Delayed diagnosis can lead to suboptimal treatment and adverse outcomes.
Purpose of the Study:
- To systematically review case reports on hepatobiliary tuberculosis.
- To analyze symptomatology, diagnostics, management, and outcomes.
- To enhance patient safety and recovery.
Main Methods:
- Systematic search of PubMed (1992-2022) for English case reports/series on hepatobiliary tuberculosis.
- Keywords: hepatobiliary, liver, tuberculosis cholangitis, cholangiopathy, mycobacterium.
- Included 17 case studies (24 cases) after initial search yielded 132 cases.
Main Results:
- Common symptoms: fever, abdominal pain, weight loss, jaundice. Objective findings: hepatomegaly, elevated liver enzymes/bilirubin.
- CT scan and ultrasound were key diagnostic tools. Histologic confirmation of *Mycobacterium tuberculosis* was definitive.
- Standard anti-TB drugs (Rifampicin, Isoniazid, Pyrazinamide, Ethambutol) were used. 18/24 cases showed improvement, 4/24 recovered.
Conclusions:
- Accurate diagnosis and prompt management are crucial for hepatobiliary tuberculosis.
- Early intervention can prevent complications and lead to recovery.
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