Related Experiment Video

Updated: Jul 11, 2025

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

19.6K

The Relationship Between Global Left Ventricular Function, as Indicated by the Tei Index, and Long-Term Survival in

M Karabacak1, A Peynirci1, O Ozdil1

  • 1Suleyman Demirel University, Department of Cardiology, Medical Faculty.

Kardiologiia
|November 16, 2023
PubMed

Insights

The Tei index, a marker of heart function, is higher in dilated cardiomyopathy (DCM) patients who die. Combining a high Tei index with low ejection fraction (EF) indicates shorter survival in DCM patients.

Area of Science:

  • Cardiology
  • Echocardiography
  • Heart Failure Research

Background:

  • Idiopathic dilated cardiomyopathy (DCM) is a primary cause of heart failure with low ejection fraction (EF).
  • The Tei index assesses left ventricular (LV) systolic and diastolic function, showing prognostic value in DCM.
  • Previous research indicates the Tei index's utility in predicting outcomes for DCM patients.

Purpose of the Study:

  • To investigate the association between the Tei index and long-term survival in non-ischemic DCM.
  • To determine if the Tei index can predict mortality in patients with DCM.

Main Methods:

  • The study included 98 patients diagnosed with non-ischemic DCM.
  • Echocardiographic Tei index and LV ejection fraction (LVEF) were measured.
  • Patient survival data was collected and analyzed over a mean follow-up of 59 months.

Main Results:

  • The Tei index was significantly higher in patients who died compared to survivors (0.71±0.12 vs 0.64±0.08, p=0.01).
  • LV end-systolic volume and LVEF were independent predictors of worse long-term survival.
  • Patients with LVEF ≥32.7% and Tei index ≤0.76 demonstrated significantly longer survival.

Conclusions:

  • The Tei index is significantly associated with mortality in non-ischemic DCM patients.
  • A combination of low LVEF (≤32.7%) and high Tei index (≥0.76) predicts a shorter life expectancy.
  • The Tei index is a potentially valuable echocardiographic tool for predicting long-term survival in DCM.
Abstract

More Related Videos

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.0K
Histological Quantification of Chronic Myocardial Infarct in Rats09:45

Histological Quantification of Chronic Myocardial Infarct in Rats

Published on: December 11, 2016

14.6K

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
11
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
14
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
15
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
16
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
14
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
15