Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Salinomycin toxicity in turkeys.

L M Potter, J P Blake, M E Blair

    Poultry Science
    |October 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Corrigendum to "Comparative efficacy of tannin-free grain sorghum varieties for the control of necrotic enteritis caused by Clostridium perfringens in broiler chickens" [Poultry Science, Volume 102, Issue 2, February 2023, 102300].

    Poultry science·2025
    Same author

    Comparative efficacy of tannin-free grain sorghum varieties for the control of necrotic enteritis caused by Clostridium perfringens in broiler chickens.

    Poultry science·2022
    Same author

    Apparent metabolizable energy, growth performance and carcass traits of Japanese quail fed select modern grain sorghum varieties.

    Animal bioscience·2022
    Same author

    Epigenetic-Imprinting Changes Caused by Neonatal Fasting Stress Protect From Future Fasting Stress.

    Journal of neuroendocrinology·2015
    Same author

    Ecological divergence and speciation between lemur (Eulemur) sister species in Madagascar.

    Journal of evolutionary biology·2013
    Same author

    Two receptors are involved in the central functions of kynurenic acid under an acute stress in neonatal chicks.

    Neuroscience·2013
    Same journal

    Assessment of freshness and oxidative stability of chicken meat patties at refrigerated storage using Dillenia indica peel powder: A natural substitute for synthetic antioxidants.

    Poultry science·2026
    Same journal

    Blood acid/base balance in poultry: Dietary, environmental, and physiological determinants and emerging diagnostic opportunities.

    Poultry science·2026
    Same journal

    Corrigendum to "Avian herpesvirus-specific LORF5 is a late gene,interacts with 19 viral and 111 host proteins, critical for virulence of Duck plague virus" [Poultry Science, Volume 105, Issue 7, July 2026, 106924].

    Poultry science·2026
    Same journal

    Assessing the impact of dietary interventions on the resistomes of broiler chickens.

    Poultry science·2026
    Same journal

    Pasture-based versus conventional broiler chicken production: Enterprise budget modeling and profitability analysis.

    Poultry science·2026
    Same journal

    Characterizing locomotor behavior variability in commercial broiler flocks using large-scale video tracking.

    Poultry science·2026
    See all related articles

    Toxicity of salinomycin in turkeys increases with age. Young turkeys showed minimal impact, while older turkeys experienced significant growth reduction and increased mortality from salinomycin exposure. Exercise caution with feed contamination.

    Area of Science:

    • Veterinary Toxicology
    • Animal Science
    • Poultry Nutrition

    Background:

    • Salinomycin is a widely used ionophore antibiotic in poultry feed for growth promotion and coccidiosis prevention.
    • Understanding the toxicological profile of salinomycin across different age groups is crucial for safe application in turkey farming.

    Purpose of the Study:

    • To investigate the age-dependent toxic effects of salinomycin in Large White male turkeys.
    • To determine the threshold levels of salinomycin that cause adverse effects in turkeys at various life stages.

    Main Methods:

    • Conducted five 7-day trials with Large White male turkeys aged 7, 11, 15, 27, and 32 weeks.
    • Administered diets containing specific concentrations of salinomycin (e.g., 22, 44, 66 ppm) to different age groups.

    Related Experiment Videos

  • Monitored and recorded mortality rates and growth performance parameters.

    • Main Results:

    • Salinomycin toxicity significantly increased with the age of the turkeys.
    • Turkeys at 27-32 weeks of age showed substantially higher mortality (13/20) when fed 44-66 ppm salinomycin compared to 7-week-old turkeys (1/84).
    • A dose of 22 ppm salinomycin depressed growth in younger turkeys and inhibited growth while increasing mortality in older turkeys.

    Conclusions:

    • Age is a critical factor influencing salinomycin toxicity in turkeys.
    • Older turkeys are more susceptible to the adverse effects of salinomycin, including mortality and growth depression.
    • Strict measures are necessary to prevent salinomycin contamination in turkey feed to avoid detrimental health impacts.