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Medication compliance of children with epilepsy: a cross-sectional survey
Shanshan Wang1, Xu Zhang1, Yongqian Wang1
1Department of Neurology, Children's Hospital of Nanjing Medical University, No. 72, Guangzhou Road, Gulou District, Nanjing, Jiangsu Province, China.
Insights
Medication compliance in children with epilepsy is often poor, affecting prognosis. Factors like age, epilepsy duration, parental education, income, and number of drugs influence compliance, requiring targeted interventions.
Area of Science:
- Pediatric Neurology
- Clinical Pharmacy
- Public Health
Background:
- Medication compliance is crucial for the long-term health outcomes of children with epilepsy.
- Poor adherence can significantly worsen the prognosis and quality of life for pediatric patients.
Purpose of the Study:
- To assess the current status of medication compliance among children with epilepsy.
- To identify key factors influencing medication adherence in this population.
- To inform clinical nursing practices for improving pediatric epilepsy management.
Main Methods:
- A study involving 156 children with epilepsy admitted to a children's hospital.
- Utilized self-designed questionnaires and a medication compliance scale.
- Employed Pearson correlation and multivariate logistic regression analyses to identify influencing factors.
Main Results:
- 37.18% of children exhibited poor medication compliance.
- Significant correlations found between compliance and age, epilepsy duration, parental education, income, and number of medications.
- Younger age, longer epilepsy duration, lower parental education, lower income, and polypharmacy were associated with poor compliance.
Conclusions:
- Medication compliance in children with epilepsy requires improvement.
- Key influencing factors include patient age, epilepsy duration, socioeconomic status, and treatment complexity.
- Targeted nursing interventions addressing these factors are essential for enhancing medication adherence.
Background:
Good medication compliance is very important for the prognosis of children with epilepsy. We aimed to evaluate the status and influencing factors of medication compliance in children with epilepsy and to provide insights to the clinical nursing care of children with epilepsy.
Methods:
We selected epileptic children admitted to Children's Hospital of Nanjing Medical University from February 1, 2022 to August 31, 2022. Self-designed questionnaire and medication compliance scale were used to evaluate the characteristics and medication compliance of children with epilepsy. Pearson correlation analysis and multivariate logistic regression were used to analyze the influencing factors of medication compliance.
Results:
A total of 156 children with epilepsy were included, the incidence of poor compliance in children with epilepsy was 37.18%. Pearson correlation analysis indicated that age(r = 0.622), courses of epilepsy(r = 0.553), parental education level(r = 0.506), monthly household income(r = 0.652) and number of drugs taken(r = 0.577) were correlated with the compliance(all P<0.05). Logistic regression analyses indicated that age ≤ 6 y(OR = 2.104, 95%CI: 1.712 ~ 2.527), courses of epilepsy ≤ 3 years(OR = 2.661, 95%CI: 2.089 ~ 2.941), low parental education level(OR = 1.977, 95%CI: 1.314 ~ 2.351), monthly household income ≤ 5000 RMB(OR = 2.812, 95%CI: 2.194 ~ 3.181), number of drugs taken ≥ 3(OR = 3.025, 95%CI: 2.336 ~ 3.475) were the influencing factors of medication compliance in children with epilepsy(all P<0.05).
Conclusions:
The medication compliance of children with epilepsy needs to be improved, and the medication compliance of children is affected by age, courses of epilepsy, parental education level, monthly household income and number of drugs taken. Clinical medical personnel take targeted nursing measures against these factors to improve the medication compliance of children with epilepsy.
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