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A Case of Pembrolizumab-Induced Papillitis With Transverse Myelitis

Nathan A Lambert-Cheatham1, Ragha C Sakuru, Melody Merati

  • 1Department of Neurology and Ophthalmology, Michigan State University, East Lansing, Michigan.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|November 17, 2023
PubMed
Abstract

No abstract available in PubMed .

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Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...