A Study Prevalence of Congenital Rubella Syndrome Cases Before and After Rubella Vaccination Campaign

Nyilo Purnami1, Hayyu Fath Rachmadhan1, In Seok Moon2

  • 1Department of Otorhinolaryngology Head and Neck Surgery (ORL-HNS), Faculty of Medicine Airlangga University, Dr. Soetomo General Academic Hospital Center, Jl. Mayjen Prof. Dr. Moestopo No. 6-8, Airlangga, Kec. Gubeng, Kota SBY, Surabaya, Jawa Timur 60286 Indonesia.

Insights

Congenital rubella syndrome (CRS) remains a concern, with hearing loss being the most common symptom. This study analyzed CRS cases before and after the Rubella Vaccination Campaign, highlighting its continued impact.

Area of Science:

  • Pediatrics
  • Public Health
  • Epidemiology

Background:

  • Rubella is a preventable disease and a primary cause of congenital disabilities.
  • Congenital Rubella Syndrome (CRS) poses a significant public health challenge, particularly in regions with varying vaccination coverage.
  • Understanding the epidemiological trends of CRS is crucial for effective public health interventions.

Purpose of the Study:

  • To identify and analyze patients diagnosed with Congenital Rubella Syndrome (CRS).
  • To compare the incidence and characteristics of CRS cases before and after the implementation of a Rubella Vaccination Campaign (RVC).
  • To evaluate the impact of the RVC on CRS prevalence in an audiology outpatient setting.

Main Methods:

  • A descriptive study design was employed.
  • Secondary data were collected from CRS surveillance case investigation forms and medical records.
  • Data spanned from 2015 to 2020 at Dr. Soetomo General Hospital Surabaya, including 346 suspected CRS cases.

Main Results:

  • Out of 346 suspected cases, 145 (41.9%) were classified as clinical CRS, 65 (18.8%) as confirmed CRS, and 136 (39.3%) as discarded CRS.
  • The majority of suspected CRS cases (27.4%) were observed in infants under one month of age.
  • Hearing loss was the most frequently reported symptom across both pre- and post-RVC periods.

Conclusions:

  • Despite the Rubella Vaccination Campaign, Congenital Rubella Syndrome continues to be diagnosed.
  • Hearing loss is a persistent and prevalent symptom associated with CRS.
  • Ongoing surveillance and vaccination efforts are essential to reduce the burden of CRS.